Cambridge Biotherapies | Ketamine, Spravato, and TMS Treatment for Depression
6 Bigelow Street, Cambridge
4.6(54 Google reviews)
United States
2 listed treatment centers serving Cambridge and the surrounding area.
Clinics in and around Cambridge offer ketamine in different ways: IV infusions, intramuscular (IM) injections, supervised oral doses, SPRAVATO® (esketamine) nasal spray, and ketamine-assisted psychotherapy. Only SPRAVATO® is FDA-approved for specific kinds of depression; other ketamine uses for mental health or pain are off-label and usually self-pay. Ask each clinic for a written price for the full course before you book.
6 Bigelow Street, Cambridge
4.6(54 Google reviews)
50 Church Street, Cambridge
5.0(19 Google reviews)
Ketamine treatment is given in a supervised clinic setting, with monitoring afterward. Arrange transportation home after each visit. Distances below are straight-line miles from Cambridge.
2.1 miles away · Brookline
1180 Beacon Street, Brookline
4.5(35 Google reviews)
2.1 miles away · Brookline
1101 Beacon Street, Brookline
5.0(8 Google reviews)
2.1 miles away · Brookline
1180 Beacon Street, Brookline
2.1 miles away · Brookline
2.4 miles away · Belmont
93 Concord Avenue, Belmont
4.0(4 Google reviews)
3.6 miles away · Boston
Before starting treatment, ask for a written estimate for the full proposed course—not just the first appointment. Clinics set their own prices, and your total may include an evaluation, medication, administration, monitoring, and follow-up visits. Ask which services are included and which are billed separately.
IV, IM, and oral ketamine are off-label for mental health treatment and are usually self-pay. The two Cambridge listings in this directory both list SPRAVATO®, so do not assume they also offer these other routes. If you are considering off-label treatment elsewhere, ask how many initial sessions are proposed, when the plan will be reassessed, and what maintenance visits could cost. A quote should explain cancellation policies and any charges if treatment is postponed or stopped.
Useful questions for the billing team include:
SPRAVATO® is the coverage exception: it is often insurance-covered after prior authorization at an in-network, certified treatment center. Coverage is not automatic. Confirm the center's network status, whether authorization covers both medication and supervised visits, and your deductible, copay, or coinsurance responsibilities. Ask who submits the authorization and what happens if it is denied. Have the clinic and insurer clarify your expected share before scheduling a course.
Treatment takes more planning than the time spent receiving medication. The two Cambridge listings in this directory both list SPRAVATO®. Confirm current appointment availability, evaluation requirements, and treatment schedules directly; a listing does not establish whether a center is accepting new patients or offers IV, IM, or oral ketamine.
For off-label IV ketamine, an initial series often involves several sessions over a few weeks. Your clinician should explain the proposed schedule and when they will review whether continuing is appropriate. Plan a ride home for every treatment visit, and do not drive until the next day after restful sleep. Ask whether the center requires a responsible adult to accompany you rather than allowing an unaccompanied hired ride.
SPRAVATO® is self-administered only in a certified healthcare setting under supervision. Each visit includes at least two hours of monitoring afterward; allow additional time for check-in, preparation, and discharge. Arrange transportation home and do not drive until the next day after restful sleep. Monitoring may last longer if the care team determines you are not ready to leave.
When planning around work, ask about appointment times and leave room for recovery rather than assuming you can immediately resume demanding tasks. Consider childcare, caregiving, and your driver's availability across the whole schedule.
People comparing Cambridge with nearby options may look in Brookline, Woburn, Newton, North Andover, Belmont, Needham, Wellesley, or West Boylston. These cities have directory listings, but routes and openings require confirmation. Whether traveling into Cambridge or elsewhere, weigh repeated travel and reliable transportation alongside appointment availability.
This directory lists two Cambridge providers, and both list SPRAVATO®. That does not confirm current openings or availability of IV, IM, or oral ketamine. Contact the centers to ask about new-patient evaluations, eligibility, and scheduling. If their schedules do not fit, you can also compare directory listings in nearby communities such as Brookline, Belmont, Newton, and Woburn.
IV ketamine is given through a vein, IM ketamine by injection into a muscle, and oral ketamine by mouth. These routes are off-label for depression and other mental health conditions. SPRAVATO® is esketamine nasal spray, FDA-approved for treatment-resistant depression and depressive symptoms in adults with major depressive disorder with acute suicidal ideation or behavior. It is self-administered only under supervision in a certified healthcare setting, not taken home.
SPRAVATO® is often covered after prior authorization at an in-network, certified center, but coverage depends on your benefits and eligibility. Ask both the center and insurer about medication charges, supervised visits, and your share of costs. IV, IM, and oral ketamine for mental health treatment are off-label and usually self-pay. Request a written full-course estimate rather than relying on a per-visit quote.
Ask whether your first appointment is an evaluation only or could include treatment. An evaluation generally reviews symptoms, previous treatments, medications, substance use, and medical history to assess suitability. Bring an up-to-date medication list and any requested records. Confirm preparation instructions and costs beforehand. If treatment is scheduled, arrange a ride home and do not drive until the next day after restful sleep.
SPRAVATO® can cause dizziness, nausea, sleepiness, dissociation—feeling disconnected from yourself or your surroundings—and increased blood pressure. Ask how the team monitors and manages these effects. Visits require at least two hours of monitoring, and you may need longer before discharge. Arrange a ride home and do not drive until the next day after restful sleep, even if you feel better sooner.
SPRAVATO® has a boxed warning for sedation, dissociation, respiratory depression, abuse and misuse, and suicidal thoughts and behaviors. Confirm that the center is certified, and ask how staff monitor breathing, blood pressure, and readiness to leave. Discuss your medical history, medications, and substance use openly. SPRAVATO® has not been shown to prevent suicide and does not replace hospitalization when clinically necessary.
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