IV ketamine
IM ketamine
Ketamine-assisted psychotherapy
SPRAVATO® (esketamine)
(443) 940-6663View profile →
Independent national directory · 522 cities
Find ketamine treatment near you
956
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53
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Monitored
Clinic-supervised dosing sessions
40–60 min
Typical IV dosing session
Provider directory
Ketamine treatment centers across the United States
Compare clinic locations, insurance information, treatment options offered, and direct contact details.
Promoted
Oasis Therapeutics - TMS and Ketamine Therapy Nashua
436 Amherst Street, Suite 100, Nashua
4.8(29 Google reviews)
(888) 871-6059View profile →
Promoted
Three Rivers Wellness - Ketamine Treatment Gallatin
1531 Hunt Club Boulevard, Suite 106, Gallatin
5.0(27 Google reviews)
(629) 276-9792View profile →
Promoted
Oasis Therapeutics - TMS and Ketamine Therapy Concord
197 Loudon Road, Unit 200, Concord
5.0(2 Google reviews)
(888) 907-7459View profile →
Acute Pain Therapies | Bellevue Ketamine, Spravato, Injections Clinic - Drs. Zachary Fisk, and Christina Julian
13033 Northeast Bel Red Road, Bellevue
4.8(589 Google reviews)
IV ketamine
SPRAVATO® (esketamine)
(425) 440-3351View profile →
Getting started
How do I get started with ketamine treatment?
Three steps. Many clinics accept self-referrals, though some ask for a referral or records from your clinician. Here is what the path from searching to your first session actually looks like.
- 01
Find a treatment center near you
Search by city or ZIP and compare locations, contact details, hours, and the treatments each clinic lists.
- 02
Book your consultation
Call the practice directly or send one short request and we pass it to clinics near you.
- 03
Complete a clinical evaluation
A qualified healthcare professional determines which treatment approach is appropriate, reviews safety risks, and discusses an individualized schedule.
Treatment options
IV, IM, and oral ketamine — every route of administration
Every route of administration
IV infusion, intramuscular injection, and oral tablets or lozenges — plus esketamine nasal spray and ketamine-assisted psychotherapy where clinics offer them. Ketamine for mood and pain conditions is used off-label; your prescriber sets the dose and protocol.
Coverage varies by route and plan
Insurance sometimes covers esketamine (SPRAVATO®), while IV, IM, and oral ketamine programs are frequently self-pay. Verify benefits with both the clinic and your plan before booking.
Clinic-supervised, never on your own
Reputable programs screen you first, monitor you throughout each session, and require a ride home. Ketamine can raise blood pressure and cause dissociation, so the setting matters.
By condition
Ketamine treatment, by condition
Our guides explain how ketamine and esketamine are used across treatment-resistant depression, anxiety, PTSD, chronic pain, OCD, and more — including what the evidence does and doesn't support.
One ketamine-based medicine — esketamine nasal spray (SPRAVATO®) — is FDA-approved, and only for adults with treatment-resistant depression or depressive symptoms with acute suicidal ideation or behavior. IV, IM, and oral ketamine are used off-label across several conditions, with evidence that ranges from strong (treatment-resistant depression) to still experimental (OCD). Every guide separates what is approved, what is promising, and what is unproven.
Even the one self-administered option — esketamine nasal spray — is dosed only in a certified clinic under a provider's supervision, and eligibility is decided by a prescriber who knows your full history — not by a quiz or a checklist.
FDA-approved (esketamine)
Treatment-resistant depression
Depression that has not responded adequately to at least two oral antidepressants. Esketamine nasal spray (SPRAVATO®) is FDA-approved for this use in adults; IV, IM, and oral ketamine are off-label options that many clinics offer.
Read the guideApproved in specific casesDepression (major depressive disorder)
Ketamine-based treatments act on glutamate, a different pathway from traditional antidepressants, and can work within hours to days for some patients. Only esketamine is FDA-approved, and only for specific depression populations; other routes are off-label.
Read the guideOff-label useAnxiety disorders
Early evidence from randomized trials and meta-analyses suggests ketamine can reduce anxiety symptoms short-term, including in people whose anxiety has resisted other treatments. All such use is off-label — no ketamine-based medicine is FDA-approved for anxiety.
Read the guideOff-label usePTSD
Ketamine is being studied and used off-label for post-traumatic stress disorder, with early trials suggesting rapid but temporary symptom reduction. Esketamine is not approved for PTSD, and treatment should be coordinated with trauma-focused therapy.
Read the guideOff-label useChronic pain
Ketamine is an FDA-approved anesthetic, but its use for chronic pain conditions — neuropathic pain, complex regional pain syndrome, fibromyalgia — is off-label. Evidence is mixed, with some support for neuropathic and CRPS pain.
Read the guideOff-label useOCD
Early research on ketamine for obsessive-compulsive disorder shows mixed and short-lived results in small trials. It remains off-label and experimental — standard care is still exposure-based therapy with SSRIs.
Read the guideWondering whether ketamine treatment is realistic for your situation? Start with a guide above, then browse clinics near you and confirm with each one what they treat and what they charge.
Browse all condition guidesBrowse by location
Find ketamine treatment by state
Most ketamine treatment means repeated in-clinic visits with monitoring and a ride home, so location matters.
Insurance & cost
What insurance actually covers for ketamine treatment
For most people, IV, IM, and oral ketamine are self-pay. No ketamine-based medicine is FDA-approved for depression, anxiety, PTSD, OCD, or chronic pain in those forms, and most insurance plans exclude off-label psychiatric use. A typical initial IV course commonly runs a few thousand dollars — confirm pricing with any clinic before you book.
IV, IM & oral ketamine — usually self-pay
Off-label for every condition, so insurers generally decline coverage. Clinics charge per session, and maintenance adds to the initial course.
How much ketamine treatment costsSPRAVATO® — often covered, with conditions
The one FDA-approved option, and only for treatment-resistant depression or MDD with acute suicidal ideation or behavior. Coverage requires prior authorization and a REMS-certified clinic.
SPRAVATO® insurance, step by stepFree, no obligation
Tell us where you are and we'll help you find a nearby treatment center
Share your town and your insurance. We match you with providers who treat your condition. Each clinic confirms its own availability, pricing, and any insurance it accepts.
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- Clinics reply to you directly
News desk
Ketamine treatment news & updates
Patient experience
How to vet a ketamine clinic: 10 questions to ask before you book
The quality gap between ketamine clinics is enormous and the industry is lightly standardized. Ten questions that separate well-run programs from storefronts.
Treatment options
Oral ketamine at home: what the evidence actually says
Clinics increasingly prescribe oral ketamine for supervised home protocols. The evidence is thinner than the marketing suggests — here's what's known, and the risks nobody mentions.
Safety
Is ketamine safe? Risks, side effects, and who should avoid it
Ketamine-based treatment is generally well tolerated in monitored settings, but the risks are real and labeled. What the boxed warnings mean, common side effects, and who should not get it.